Protein S (8D5) Antibody

h1 class=titleProtein S (8D5) Antibody/h1
div id=node-597 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250397/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pProtein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 micro;g/ml, with a half-life of approximately two days. About 40% of protein S in plasma is in a free form, wheraes 60% is complexed with C4b-binding Protein (C4BP). Only the free protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa. This antibody is specific for human protein S./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pVitamin K-dependent protein S; PROS1; PROS/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P07225P07225/abr /
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h4Clonality/h4
p8D5/p
h4Antigen/h4
pnbsp;/p
pProtein S isolated from human plasma/p
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h4Application Notes/h4
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pProduct Cat. No. 250397 reacts strongly in sandwich ELISA with protein S and a biotin-labeled antibody. Antibody binding is calcium-dependent and is optimal at 1 mM CaCl2 in Tris buffer. SDS-treatment abolishes the reactivity in dot blot.nbsp;/p
pE: 1:20,000/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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