Protein Disulfide Isomerase (PDI) (Mouse) ELISA Kit

Alternate Name :

Tag Line :

A Sandwich ELISA kit for the quantitative measurement of Protein Disulfide Isomerase in mouse serum, plasma, culture supernatants and other biological fluids.

Storage Conditions: 4°C

Shelf life: 6 months

Summary :

• Detection method- Absorbance (450 nm)
• Species reactivity- Mouse
• Application- quantitative measurement of PDI in Mouse serum, plasma, tissue homogenates and other biological fluids.

Detection Method: Absorbance (450 nm)

Features & Benefits:

Easy, convenient and time-saving method to measure the level of PDI in mouse serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
Detection Range: 0.156 - 10 ng/ml
Sensitivity: < 0.094 ng/ml
Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%

Description:

Protein Disulfide Isomerases are multifunctional proteins that constitute a thio-disulfide oxidoreductase family. PDI is abundant in the lumen of endoplasmic reticulum and it plays an essential role in catalyzing the rearrangement of disulfide (S-S) bonds in proteins and functions as a chaperone by inhibiting protein aggregation. Recent studies show that PDI activity is essential for cancer cell survival and proliferation, and targeting PDI activity with specific inhibitors abrogates survival responses leading to ER stress in cancer cells. Therefore, the detection of PDI activity is critical for mechanistic study, diagnosis, prevention, and therapeutic purposes. BioVision’s Protein Disulfide Isomerase ELISA kit is a sandwich ELISA assay for the quantitative measurement of mouse PDI in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of mouse PDI captured from the samples.