ProInsulin Antibody

Antibody Target :ProInsulin

Host: Mouse

Antibody Type: Monoclonal

Isotype: Mouse IgG1

Antibody Form: Affinity Purified Antibody

Immunogen Sequence: Recombinant full length insulin

Accession#: P01308

Gene ID: 3630

Appearance: Colorless liquid

Concentration: 1.0 mg/ml

Formulation: 100 µg (1.0 mg/ml) purified mouse monoclonal antibody supplied in PBS with 0.05% (W/V) sodium azide.

Purification: Affinity purified

Species Reactivity: hu/bv/pg

Application: Indirect ELISA/WB/IHC

Application & Usage: The antibody can be used for indirect ELISA, WB and IHC.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: Proinsulin is a prohormone precursor to Insulin, made by the pancreas in response to increased blood sugar. Proinsulin is 39 amino acids longer than the mature Insulin, of which 4 are completely lost and the remaining 35 forms the C-peptide. The measurement of Proinsulin in serum provides a useful, valuable information for the diagnosis of insulinomas. Proinsulin levels have also been shown to be elevated in non-insulin dependent diabetics (NIDDM), in insulin dependent diabetics (IDDM) and other clinical situations. The antibody recognizes insulin and recombinant proinsulin, but does not react with synthetic C-peptide.