Presenilin 2 Antibody
- 貨號 Cat. No.
- 3482-100
- 規格 Size
- 100 µg
Description
Antibody Target :Presenilin 2
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Antibody Form: Affinity Purified Antibody
Immunogen Sequence: Synthetic peptide surrounding amino acid 333 of human presenilin 2
Accession#: NP_036618
Gene ID: 5664
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification: Affinity purified
Species Reactivity: hu/ms/rt
Application: WB/IHC/IP
Application & Usage: Western blotting (2-4 µg/ml), immunoprecipitation (20 µg/ml), and immunohistochemistry (20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes Presenilin 2 of human, mouse, and rat origins. Reactivity to other species has not been tested.
Storage Temp.: -20 °C
Shipping : gel pack
Shelf Life: 12 months
Handling: The antibody solution should be gently mixed before use.
Brief Background Descriptions: Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer’s disease, probably functioning through its associated g-secretase activity for amyloid-β protein processing. Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed N-terminal (34 kDa) and C-terminal (~20 kDa) fragments.