Prasugrel

貨號 Cat. No.: S1258
規格 Size: 25mgã€100mgã€300mg
品牌 Brand: Selleckchem

Description

Prasugrel

Catalog No.S1258

A novel platelet inhibitor

Size

Price

Stock

Quantity

25mg	USD 151	In stock	0 1 2 3 4 5 6 7 8 9 10
100mg	USD 466	In stock	0 1 2 3 4 5 6 7 8 9 10
300mg	USD 970	In stock	0 1 2 3 4 5 6 7 8 9 10

Distributor Tel: +886-2-2827-1197jimmy@new.abscience.com.tw

Biological Activity

Prasugrel is a novel platelet inhibitor used for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome who are to be managed with PCI. [1]

Prasugrel reduces the aggregation ("clumping") of platelets by irreversibly binding to P2Y12 receptors. In rat platelets, prasugrel AM inhibited in vitro platelet aggregation induced by ADP (10 μm) with an IC50 value of 1.8 μm. [2]

Clinical Trial Information( data from http://clinicaltrials.gov)

NCT Number	Recruitment	Conditions	Sponsor /Collaborators	Phases
NCT02108808	Recruiting	Fractional Flow Reserve	University of Patras	Phase 4
NCT02118870	Not yet recruiting	Acute Coronary Syndrome	Diagram B.V.	Phase 4
NCT02016170	Recruiting	Coronary Artery Disease\|Acute Coronary Syndrome	University of Florida
NCT02065479	Recruiting	Coronary Artery Disease	University of Florida	Phase 4
NCT02081443	Not yet recruiting	Coronary Artery Disease	University of Florida\|The Medicines Company

Chemical Information

Download Prasugrel SDF

Molecular Weight (MW)	373.44
Formula	C20H20FNO3S
CAS No.	150322-43-3

Storage	3 years -20â„ƒPowder
Storage	6 months-80â„ƒin DMSO
Syonnyms	Effient, Efient, Prasita

Solubility (25°C) *	In vitro	DMSO	30 mg/mL (80 mM)
		Water	<1 mg/mL (<1 mM)
		Ethanol	7 mg/mL (18 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.