PP242

Alternate Name/Synonyms: 2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1092351-67-1

Molecular Formula: C₁₆H₁₆N₆O

Molecular Weight: 308.34

Purity: ≥98% by HPLC

Solubility: DMSO (>50 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (ICâ‚…â‚€ = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin (Cat. No. 1568-5 & 1568-50).

Handling: Protect from air and light