PLC gamma 2 Antibody
- 貨號 Cat. No.
- 3587-100
- 規格 Size
- 100 µg
Description
Antibody Target :PLCg2
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Antibody Form: Affinity Purified Antibody
Immunogen Sequence: Synthetic peptide near the C-terminus of human PLCg2
Accession#: AAH18646
Gene ID: 5336
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
Purification: Affinity purified
Species Reactivity: hu/ms/rt
Application: WB/IP/IHC
Application & Usage: Western blotting (1-4 µg/ml), immunoprecipitation (20 µg/ml), and immunohistochemistry (20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 150 kDa PLCg2 in samples from human, mouse, and rat origins. The antibody does not cross-react with PLCg1.
Storage Temp.: -20 °C
Shipping : gel pack
Shelf Life: 12 months
Handling: The antibody solution should be gently mixed before use.
Brief Background Descriptions: PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCg2 is engaged in antigen-dependent signaling in B-cells and collagen-dependent signaling in platelets.