PID/MTA2 Antibody

Antibody Target :PID/MTA2

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen Sequence: Synthetic peptide corresponding to residues surrounding amino acid 655 of human PID/MTA2

Accession#: NP_004730

Gene ID: 9219

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) immunopaffinity purified rabbit anti-PID/MTA2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification: Affinity purified

Species Reactivity: hu/ms/rt

Application: WB

Application & Usage: Western blotting (1 µg/ml). An approximately 75 kDa band can be detected. HeLa cell lysate can be used as a positive control. No cross-reactivity to MTA1.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: PID/MTA2, also termed MTA1-L1, is a novel molecule that has been found to be involved in p53 pathway. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylastion of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues.