Phospho-Tyrosine Hydroxylase Antibody

Antibody Target :Phospho-Tyrosin Hydroxylase

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen Sequence: Synthetic phospho-peptide correspondign to residues surrounding Ser40 of human Tyrosine Hydroxylase

Accession#: AAI04968

Gene ID: 7054

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µl antigen affinity purified rabbit anti-phospho-Tyrosine Hydroxylase polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% Thimerosal.

Purification: Affinity purified

Species Reactivity: hu/ms/rt

Application: WB/IF/IHC

Application & Usage: Western blotting (1:200-1000) and immunofluorescence (1:50-100). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects a ~60 kDa Tyrosine Hydroxylase when phosphorylated at Ser40.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: Tyrosine hydroxylase play an important role in the synthesis of dopamine and other catecholamines. The enzyme’s activity is regulated in the level of transcription and translation, as well as posttranscriptional modifications. Phosphorylation at Ser40 may play a key role in regulation of the catalytic activity of the enzyme.