Phospho-IRS (Ser616) Antibody
- 貨號 Cat. No.
- 3105-100
- 規格 Size
- 100 µg
Description
Antibody Target :Phospho-IRS
Host: Mouse
Antibody Type: Monoclonal
Isotype: Mouse IgG1
Antibody Form: Affinity Purified Antibody
Immunogen Sequence: Synthetic peptide phosphorylated at Ser 616 site
Accession#: P35568
Gene ID: 3667
Appearance: Colorless liquid
Concentration: 1.0 mg/ml
Formulation: 100 µg (1.0 mg/ml) purified mouse monoclonal antibody supplied in PBS with 0.05% (W/V) sodium azide.
Purification: Affinity purified
Species Reactivity: hu
Application: Indirect ELISA/WB
Application & Usage: The antibody can be used for indirect ELISA and WB.
Storage Temp.: -20 °C
Shipping : gel pack
Shelf Life: 12 months
Handling: The antibody solution should be gently mixed before use.
Brief Background Descriptions: Insulin receptor substrates (IRS) subtypes are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. The balance between Ser/Thr phosphorylation of IRS has been demonstrated to be an important regulator of insulin signaling. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm’s tumors, and adrenal cortical carcinomas. Does not recognize IRS peptide NOT phosphorylated at Ser616 and will not recognize IRS peptide phosphorylated at Tyr183. Also does not react with riboflavin carrier protein which is known to have multiple phosphate groups.