Phospho-GSK-3a Antibody

貨號 Cat. No.
3516-100
規格 Size
100 µg

Description

pstrongAntibody Target :/strongPhospho-GSK-3a/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bSynthetic phospho-peptide derived from human GSK-3a/p
pbAccession#: /bNP_063937/p
pbGene ID: /b2931/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity-purified rabbit polyclonal phospho-GSK-3??? (Ser21/9) polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/ms/rt/p
pbApplication: /bWB/IHC/p
pbApplication amp; Usage: /bWestern blot analysis (1-2 micro;g/ml), and immunohistochemistry (20-30 micro;g/ml). However, the optimal conditions should be determined individually. The phospho-GSK-3alpha;/beta; (Ser21/9) antibody detects GSK-3 only when phosphorylated at Ser21 of GSK-3alpha; or Ser9 of GSK-3beta;./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bGSK-3 is a serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3alpha; and Ser9 of GSK-3beta;./p

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