Phorbol-12-myristate 13-acetate (PMA)
- 貨號 Cat. No.
- 1544-5
- 規格 Size
- 5 mg
Description
Alternate Name/Synonyms: PMA, 12-O-Tetradecanoylphorbol 13-acetate,TPA, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
Appearance: White solid
Formulation: N/A
CAS Number: 16561-29-8
Molecular Formula: C₃₆H₅₆O₈
Molecular Weight: 616.83
Purity: >99%
Solubility: DMSO or EtOH
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: This is the most commonly used phorbol ester. It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues and is a very potent mouse skin tumor promoter. Inhibits apoptosis induced by the Fas antigen, but induced apoptosis in HL-60 promyelocytic leukemia cells
Handling: Protect from light