PF-562771
Chemical Compounds
- 貨號 Cat. No.
- M3778
- 規格 Size
- 5mg,10mg,50mg
- 品牌 Brand
- No Brand
Description
AP23464 and PF-562771 (AP23848) potently and selectively target activation-loop mutants of Kit in vitro and in vivo and could have therapeutic potential against D816V-expressing malignancies. Src/Abl inhibitors are compatible with imatinib and suggest that combined Abl inhibitor therapy is a feasible treatment strategy for patients with CML.
