PF-477736
Chemical Compounds
- 貨號 Cat. No.
- M1764
- 規格 Size
- 10mg,50mg
- 品牌 Brand
- No Brand
Description
PF-477736 is a selective checkpoint kinase 1 (Chk1) inhibitor with Ki values of 0.49 nM and 47 nM for CHK1 and CHK2 respectively.A proprietary compound PF-477736 targets cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiation activity.Chk1 inhibitor PF-477736 inhibits chk1, an ATP-dependent serine-threonine kinase that is a key component in the DNA replication-monitoring S/G2 checkpoint system.
