PerOx (TOS/TOC) (Oxidative Capacity) colorimetric

An overproduction of oxygen radicals or insufficient antioxidative capacity leads to
a dangerous imbalance in the organism. This starts pathological mechanisms which
develop several diseases. The most important disease is the cardiovascular arteriosclerosis.
Beside this inflammation processes, sepsis, cancerogenesis and neurodegenerative
diseases are postulated.
This is the reason why the determination of the oxidative status/oxidative stress
is of fundamental importance in medical diagnosis and in research. The methods
used for measurement of radical-linked effects (lipid peroxidation) up to now are
very time consuming (HPLC) or reflect only breakdown products of multiple unsaturated
fatty acids (TBARS).
The PerOx assay is fast, reliable and easy to perform. Total lipid peroxides are measured.
Because of a direct correlation between oxygen radicals and lipid peroxides,
it is possible to measure and characterize the oxidative status/oxidative stress in
biological fluids.