Perifosine (KRX-0401)

Alternate Name/Synonyms: KRX-0401

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 157716-52-4

Molecular Formula: C₂₅H₅₃NO₄P

Molecular Weight: 462.66

Purity: ≥99%

Solubility: Hâ‚‚O (10 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is induced in a time- and dose-dependent manner in U937 and Jurkat T human leukemia cell lines but not in normal vascular endothelial cells.

Handling: Protect from light and moisture