Perforin Antibody
- 貨號 Cat. No.
- 3287-100
- 規格 Size
- 100 µg
Description
Antibody Target :Perforin
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Antibody Form: Affinity Purified Antibody
Immunogen Sequence: Recombinant rat perforin
Accession#: AAH89808
Gene ID: 50669
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-Perforin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification: Affinity purified
Species Reactivity: ms/rt
Application: WB
Application & Usage: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects both mouse and rat perforin. Cross activity to perforin of other species has not been determined.
Storage Temp.: -20 °C
Shipping : gel pack
Shelf Life: 12 months
Handling: The antibody solution should be gently mixed before use.
Brief Background Descriptions: Perforin (Pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte (CTL). It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL which represents an important mechanism in the immune defense against tumors and virus infection.