Peptide YY Antibody

h1 class=titlePeptide YY Antibody/h1
div id=node-439 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250241/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
h4Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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pspan class=inline lefta href=http://www.abbiotec.com/image/peptide-yy-staining-intestineimg class=image image-_original title=Peptide YY staining in intestine: Paraffin-embedded human small intestine is stained with Peptide YY Antibody (Cat. No. 250241) used at 1:200 dilution. alt=Peptide YY staining in intestine: Paraffin-embedded human small intestine is stained with Peptide YY Antibody (Cat. No. 250241) used at 1:200 dilution. width=294 height=300 src=http://www.abbiotec.com/files/images/250241_intestine.jpg //aspan style=width: 292px class=captionstrongPeptide YY staining in intestine: /strongParaffin-embedded human small intestine is stained with Peptide YY Antibody (Cat. No. 250241) used at 1:200 dilution./span/span/p
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h4Description/h4
pPYY (peptide tyrosine-tyrosine amide) is a 36 amino-acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.nbsp; This antibody binds human PYY. Cross-reactivity with NPY or PP in solution was lt;0.1%./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/neuropeptide-y-antibody250240 Neuropeptide Y Antibody/abr /
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h4Alternate Names/h4
pPYY; PYY-1; Peptide tyrosine tyrosine/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P10082P10082/abr /
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h4Clonality/h4
pNA/p
h4Antigen/h4
pnbsp;/p
pSynthetic human PYY coupled to carrier with glutaraldehyde adsorbed onto aluminum hydroxide gel and emulsified in Freund's incomplete adjuvant./p
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h4Application Notes/h4
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pProduct Cat. No. 250241 binds free PYY in solution. Product Cat. No. 250241 reacts in ELISA with PYY coated directly onto the microtiter well. The antibody is used in IHC with paraffin-embedded tissues./p
pE: 1:16,000/p
pIHC: 1:100-1:500/p
pstrongReacts with/strongnbsp; :H/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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