PepMix™ SARS-CoV-2 (S-RBD)

Pool of 53 peptides derived from a peptide scan (15mers with 11 aa overlap) through Receptor Binding Domain of Spike Glycoprotein (Swiss-Prot ID: P0DTC2, region: 319-541) of SARS-CoV-2 (Severe Acute Respiratory Syndrome-related coronavirus 2).

Amount: 25 ug (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 10⁸ cells)
Purity: crude (major peak by LC-MS is guaranteed to be peptide of interest for each peptide)
Delivery Format: Freeze-dried in glass vial
Indication(s)/Topic(s): Covid-19, Infection, Respiratory infection
Delivery Time: 2-5 days

 

PepMix™ Peptide Pools
Protein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for
- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, cytokine staining, cell-mediated cytotoxicity or proliferation assays)
- In-vitro T cell expansion
- Dendritic cell pulsing
- Immune monitoring
- Cellular immune response profiling
- T cell epitope identification
- Standardization of T cell assays

 

Benefits of PepMix™
- Produced under stringent ISO 9001 regulations
- Each peptide quality controlled and guaranteed for identity and purity
- CoA and HPLC-MS data available for each individual peptide batch
- High batch-to-batch consistency
- No false positive T cell responses by contaminating deletion peptides
- No toxic inhibition of T cell responses due to stringent purification of each peptide
- Minimization of endotoxin contamination due to low bioburden process
- ADCF policy in place
- HLA independent stimulation (only for antigen spanning peptide pools)