Pentraxin 3 (PTX3) ELISA

pPentraxin 3 (PTX3) ELISA/p
pimg alt=For Research Use Only src=http://www.alpco.com/img/ruo.gif align=absMiddle / For Research Use Only/p
div class=prod_head_infohr /
/div
div class=prod_spec_box
div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
/div
div class=prod_spec_box
div class=prod_specSample Type:/div
div class=prod_spec_infoplasma, cell culture/div
/div
div class=prod_spec_box
div class=prod_specbSample Size:/b/div
div class=prod_spec_info10 micro;l/div
/div
div class=prod_spec_box
div class=prod_specbSize:/b/div
div class=prod_spec_info96 wells/div
/div
div class=prod_spec_box
div class=prod_specbRange:/b/div
div class=prod_spec_info0.5 - 20 ng/mls/div
/div
div class=prod_spec_box
div class=prod_specbSensitivity:/b/div
div class=prod_spec_info0.1 ng/ml/div
/div
div class=prod_spec_box
div class=prod_specbIncubation Time:/b/div
div class=prod_spec_info2 hour(s)/div
div class=prod_spec_infonbsp;/div
div class=prod_spec_infonbsp;
pbSummary:/b/p
Human Pentraxin3 / TSG-14 ELISA System is a solid-phase sandwich immunoassay (ELISA) capable of measuring human PTX3 levels in plasma and serum free cell culture supernatant. Pentraxins are a superfamily of conserved proteins characterized by the pentraxin domain. C-reactive protein (CRP) and serum amyloid protein (SAP) are recognized as classical short pentraxins, whereas pentraxin3 (PTX3) belongs to the long pentraxins. CRP and SAP are induced in the liver in response to IL-6. In contrast, PTX3 is produced by a variety of tissues and cells, such as vascular endothelial cells, macrophages, and neutrophils, predominantly in response to proinflammatory signals (bacterial products, IL-1, and TNF). PTX3 has also been observed in human atherosclerotic lesions of autopsy samples by immunohistochemistry, in association with macrophage and neutrophils infiltration. This localized expression pattern of PTX3 is believed to be indicative of primary inflammation stimuli, in contrast to CRP which is induced via secondary signals.
pnbsp;/p
/div
/div
pnbsp;/p