Penta-ubiquitin (Ub5)
- 貨號 Cat. No.
- UC-216
- 規格 Size
- 25 μg
- 品牌 Brand
- Boston Biochem
Description
Penta-ubiquitin (Ub5)
human recombinant
Product Information
25 μg
43 kDa
> 90% by SDS-PAGE
Aqueous solutions up to 5 mg/ml
This is a lyophilized powder
Use & Storage
Typical concentrations will depend on specific assay conditions and method of detection.
Solubilized solution at –20°C. Avoid multiple freeze/thaw cycles.
Catalog #: UC-216
Penta-ubiquitin (Ub5)
Product Source:
human recombinant
Linkage specific penta-Ub can be used to investigate mechanism of binding and recognition by E1 or E2 enzymes, deubiquitinating enzymes, E3 ligases, the proteasome or other proteins that contain ubiquitin-associated domains (UBAs) or ubiquitin-interacting motifs (UIMs). This product is formed with wild-type ubiquitin and linkage-specific enzymes. It has been shown that the rate of ubiquitin-substrate conjugate degradation is related to polyubiquitin chain length. Tetra-ubiquitin is the minimal unit required for recognition by the proteasome, and longer chains probably have enhanced binding to proteasomal subunits and may be more resistant to disassembly by a proteasome-associated isopeptidases.
Product Information
Quantity:
25 μg
MW:
43 kDa
Purity:
> 90% by SDS-PAGE
Solubility:
Aqueous solutions up to 5 mg/ml
Supplied:
This is a lyophilized powder
Use & Storage
Use:
Typical concentrations will depend on specific assay conditions and method of detection.
Storage:
Solubilized solution at –20°C. Avoid multiple freeze/thaw cycles.