Paxillin Antibody
- 貨號 Cat. No.
- 3448-100
- 規格 Size
- 100 µg
Description
Antibody Target :Paxillin
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Antibody Form: Affinity Purified Antibody
Immunogen Sequence: Synthetic peptide corresponding to residues near the C-terminal sequence of human Paxillin
Accession#: AAI44411
Gene ID: 219521560
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide.
Purification: Affinity purified
Species Reactivity: hu/ms/rt
Application: WB
Application & Usage: Western blotting (1-2 µg/ml). However, the optimal concentrations should be determined individually.
Storage Temp.: -20 °C
Shipping : gel pack
Shelf Life: 12 months
Handling: The antibody solution should be gently mixed before use.
Brief Background Descriptions: Paxillin is one of the key components of integrin signaling. Tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal reorganization. Paxillin is phosphorylated by another focal adhesion component, focal adhesion kinase (FAK), at tyrosine 118. Phospho-Tyr118 may provide a docking site for recruitment of other signaling molecules to focal adhesions.