PAI-1 Antibody

Antibody Target :PAI-1

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen Sequence: Recombinant rat PAI-1

Accession#: P20961

Gene ID: 24617

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) protein A affinity purified rabbit anti-PAI-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 0.1% BSA, 0.02% thimerosal.

Purification: Affinity purified

Species Reactivity: rt

Application: WB

Application & Usage: Western blot analysis (1-2 µg/ml). However, the optimal conditions should be determined individually. The antibody detects rat PAI-1. Cross reactivity of the antibody to other species has not been determined.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: PAI-1 (plasminogen activator inhibitor-1) is originally cloned from human endothelial cell and rat hepatoma cell cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI-1 inhibits both tissue-type palsminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA). High PAI-1 levels are associated with an increased risk of thromboembolic disease while PAI-1 deficiency may represent an inherited autosomal recessive bleeding disorder.