P73 alpha Antibody
Antibodies
- 貨號 Cat. No.
- 251885
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC
- Reactivity
- Human 、 Mouse
Description
***DISCONTINUED***
Tumor protein p73 (P73 alpha) participates in the apoptotic response to DNA damage. P73 isoforms containing the transactivation domain are pro-apoptotic, while isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. In contrast to p53, p73 alpha is not frequently mutated in cancers.
Tumor protein p73 (P73 alpha) participates in the apoptotic response to DNA damage. P73 isoforms containing the transactivation domain are pro-apoptotic, while isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. In contrast to p53, p73 alpha is not frequently mutated in cancers.