p53NIDP1 Antibody

Antibody Target :p53DINP1

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen Sequence: Synthetic peptide mapping to the N-terminus of human p53DINP1

Accession#: Q96A56

Gene ID: 94241

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg(0.5 mg/ml) affinity purified rabbit anti-p53DINP1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Species Reactivity: hums/rt

Application: WB/IHC

Application & Usage: Western blotting (0.5-4 µg/ml) and immunohistochemistry (5-10 µg/ml). However, the optimal dilution conditions should be determined individually. Human Lung tissue lysate can be used as a positive control. The antibody detects the 27 kDa p53DINP1-α in human, mouse, and rat samples. A lower band (~18 kDa) which represents the p53DINP1-β was also detected in certain tissue and cells.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: p53DINP1 (p53-dependent damage-inducible nuclear protein 1) encodes two proteins termed p53DINP1-α (27 kDa) and p53DINP1-β (18 kDa). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1 is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.