p21 Antibody
Antibodies
- 貨號 Cat. No.
- 251259
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC
- Reactivity
- Canine 、 Human 、 Mouse
Description
Cyclin-dependent kinase inhibitor 1 (p21 or WAF1) is an important intermediate by which TP53/p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. P21 binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.
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