Osteoprotegerin (OPG) ELISA

pOsteoprotegerin (OPG) ELISA/p
pimg alt=For Research Use Only align=absMiddle src=http://www.alpco.com/img/ruo.gif / For Research Use Only/p
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div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
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div class=prod_specSample Type:/div
div class=prod_spec_infoserum, plasma, cell culture/div
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div class=prod_specbSample Size:/b/div
div class=prod_spec_info50 micro;l/div
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div class=prod_specbSize:/b/div
div class=prod_spec_info96 wells/div
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div class=prod_specbRange:/b/div
div class=prod_spec_info1.1 - 30 pmol/l/div
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div class=prod_specbSensitivity:/b/div
div class=prod_spec_info0.14 pmol/l/div
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div class=prod_specbIncubation Time:/b/div
div class=prod_spec_infoOvernight/div
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pbSummary:/b/p
Osteoprotegerin (OPG) ELISA is an enzyme immunoassay intended for the quantitative determination of OPG in Plasma, Serum or Cell Culture supernatants. OPG is a dimeric glycoprotein of the tumor necrosis factor (TNF) receptor family that acts as a solublle receptor for sRANKL (soluble receptor-activated NF-kB ligand) and prevents it from binding to and activating RANK, thus inhibiting osteoclast development. Possible indications for OPG include the study of bone metabolism, osteoporosis, arthritis and oncology. Some recent emphasis has also been placed on the potential role of OPG and sRANKL in vascular calcification.
pbLiterature References:/b/p
img alt= src=http://www.alpco.com/img/black_bullet.gif /a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieveamp;db=PubMedamp;list_uids=12124406amp;dopt=AbstractWhyte MP, Obrecht SE, Finnegan PM, Jones JL, Podgornik MN, McAlister WH, and Mumm S. Osteoprotegerin deficiency and juvenile pagetrsquo;s disease. NJEM . 2002; 347(3):175-184./abr /
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img alt= src=http://www.alpco.com/img/black_bullet.gif /a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieveamp;db=PubMedamp;list_uids=12528762amp;dopt=AbstractSigurdardottir V, Fagerberg B, and Hulthe J. Circulating oxidized LDL is associated with risk factors of the metabolic syndrome and LDL size in clinically healthy 58-year-old men (AIR STUDY). Journal of Internal Medicine. 2002; 252: 440-447./abr /
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img alt= src=http://www.alpco.com/img/black_bullet.gif /a href=http://jn.nutrition.org/cgi/content/abstract/132/7/1879Sharman, MJ. Kraemer WJ. Love DM, Avery NG, Gomez AL, Scheett TP, and Volek JS. Ketogenic Diet Favorably Affects Serum Biomarkers for Cardiovascular Disease in Normal Weight Men. American Society for Nutritional Sciences. 2002; 1879-1885./abr /
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img alt= src=http://www.alpco.com/img/black_bullet.gif / Fukumoto F, Shoji T, Emoto M, Kawagishi T, Okuno Y, and Nishizawa Y. Antibodies Against Oxisized LDL and Carotid Artery Intima-Media Thickness in a Healthy Population. American Heart Association. 1999; 703-707.br /
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img alt= src=http://www.alpco.com/img/black_bullet.gif / Hegedus D, Ferencz V, Lakatos PL, Meszaros S, Laktos P, Horvath C, and Szalay F. Decreased Bone Density, Elevated Serum Osteoprotegerin and B-cross Laps in Wilson Disease. Journal of Bone and Mineral Research. 2002; (17)11, 1961-1967.br /
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img alt= src=http://www.alpco.com/img/black_bullet.gif /a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieveamp;db=PubMedamp;list_uids=12810175amp;dopt=AbstractJudlacek S, Schneider B, Woloszczuk W, Pietschmann P, and Willvonseder R. Serum Levels of Osteoprotegerin Increase with Age in a Healthy Adult Population. Bone. 2003; 32, 681-686./abr /
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img alt= src=http://www.alpco.com/img/black_bullet.gif / Fahrleitner A, Prenner G, Leb G, Tscheliessnigg KH, Piswanger-Solkner C, Obermayer-Pietsch B, Portugaller HR, Berghold A , and Dobnig H. Serum Osteoprotegerin is a major determinant of bone density development and prevalen vertebral fracture status following cardiac transplantation. 2003; 32, 96-106.br /
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