Osteocalcin (1-43/49) ELISA

pOsteocalcin (1-43/49) ELISA/p
pimg alt=For Research Use Only align=absMiddle src=http://www.alpco.com/img/ruo.gif / For Research Use Only/p
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div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
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div class=prod_specSample Type:/div
div class=prod_spec_infoSerum, Plasma/div
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div class=prod_specbSample Size:/b/div
div class=prod_spec_info25 micro;l/div
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div class=prod_specbSize:/b/div
div class=prod_spec_info96 Wells/div
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div class=prod_specbRange:/b/div
div class=prod_spec_info0 - 64 ng/ml/div
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div class=prod_specbSensitivity:/b/div
div class=prod_spec_info0.31 ng/ml/div
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div class=prod_specbIncubation Time:/b/div
div class=prod_spec_info1 Hour 20 Min/div
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pbSummary:/b/p
pThis ELISA uses a two-site sandwich antibody technique to specifically measure both the intact (1-49) and n-terminal mid-fragment (1-43) circulating forms of osteocalcin in human Serum and Plasma./p
pIntact osteocalcin is prone to degradation, both endogenously and after sample collection; the 1-43 fragment is more stable than the intact molecule, making the combined measurement less susceptible to differences caused by degradation of the intact molecule over time (as well as controlling for differences in sample processing and handling)./p
pIn addtion, the ratio of the fragment (1-43) to intact (1-49) may differ from sample to sample, so measuring the total pool may be more meaningful from a physiological standpoint/p