OpeRATOR Lyophilized

OpeRATOR (OgpA) is an O-glycan-specific protease that digests the protein backbone of proteins and peptides carrying core 1 mucin-type O-glycans. The OpeRATOR enzyme digests N-terminally of the O-glycosylated serine (Ser) or threonine (Thr) residue for O-glycan profiling and mapping of O-glycan sites. OpeRATOR has limited activity on core 3 O-glycosylated sites and the performance is optimal after desialylation using SialEXO. OpeRATOR is available as lyophilized powder for digestion of 2 mg of O-glycoprotein and supplied with lyophilized SialEXO for preparative desialylation.