Okadaic acid

Alternate Name/Synonyms: OA

Appearance: White solid

Formulation: N/A

CAS Number: 78111-17-8

Molecular Formula: C₄₄H₆₈O₁₃

Molecular Weight: 805

Purity: >98%

Solubility: DMSO (>1 mg/ml) and EtOH (>1 mg/ml)

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: A Potent inhibitor of protein phosphatases 1 and 2A in numerous cell types. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Non-phorbol type tumor promoter. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells, but inhibits glucocorticoid-induced apoptosis in T-cell hybridomas.

Handling: Protect from moisture. Tumor promoter