Nurr1 Antibody

h1 class=titleNurr1 Antibody/h1
div id=node-1350 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong250795/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pNuclear receptors and transcription factors play a role in the development and maintenance of neurons that synthesize thenbsp; neurotransmitter dopamine. The NURR1 gene encodes a 67-kDa member of the steroid-thyroid hormone-retinoid receptor superfamily.nbsp; The orphan nuclear receptor NURR1 may function as a general coactivator of gene transcription and transcription factor. Mutations in Nurr1 have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophrenia, and maniac depression. Misregulation of Nurr1 may be associated with rheumatoid arthritis./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pNuclear receptor subfamily 4 group A member 2; Orphan nuclear receptor NURR1; Immediate-early response protein NOT; Transcriptionally-inducible nuclear receptor; NR4A2; NOT; NURR1; TINUR/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P43354P43354/abr /
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h4Clonality/h4
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NURR1./p
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h4Application Notes/h4
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pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H | M | R/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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