NUDT1 Antibody

7,8-dihydro-8-oxoguanine triphosphatase (NUDT1) is an Antimutagenic. enzyme responsible for preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. A polymorphism between Met-1 and Met-19 removes a stop codon before the initiation codon for isoform p22 and gives rise to the production of isoform p26. The allele frequency of isoform p26 is about 20%.