NRF2(ARE) EMSA Kit

Transcription factors (TFs) are a group of cellular proteins that control gene expression. Once a TF is activated, it binds to its corresponding cis-element within promoter regions and mediates the expression of its target gene. Electrophoretic Mobility Shift Assay (EMSA) is a commonly used method for monitoring the activation of a TF in vitro. Each Signosis’ EMSA Kit is a ready-made kit including all of the reagents and transfer membranes. The included probe has been designed based the reported TF consensus sequence in well-known publications and can be used to detect the activity of a TF in human, mouse and rat samples.