Proteins and Peptides
NR3C2 Antibody (LS-B3162)
- 貨號 Cat. No.
- LS-B3162
- 規格 Size
- 50 µl
- 品牌 Brand
- LSBio
Description
| Antibody Catalog ID: | LS-B3162 |
|---|---|
| Antibody Validation: | This antibody replaces catalog number LS-C25630. It has been validated for use in the following assays: IHC-P. |
| Antibody Target: | NR3C2 |
| Synonyms: | NR3C2 Antibody, Aldosterone receptor Antibody, FLJ41052 Antibody, MCR Antibody, MGC133092 Antibody, Mineralocorticoid Receptor Antibody, Mineralocorticoid receptor Antibody, MLR Antibody, MR Antibody, nr3c2 Antibody, NR3C2VIT Antibody |
| Family: | NHR |
| Subfamily: | NR3 Steroid receptor |
| Host: | NR3C2 antibody was produced in Mouse |
| Antigen Species: | NR3C2 antibody was raised against Human |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Antibody Clone Name: | H10E4C9F |
| Antigen Type: | Hapten |
| Immunogen: | NR3C2 antibody was raised against aldosterone. |
| Antibody Specificity: | Recognizes human MR (mineralocorticoid receptor). Detects a band of ~116kD by Western Blot. Species cross-reactivity: Rat, rabbit and chicken. |
| Predicted Species Reactivity: | Chicken, Rabbit, Rat |
| Purification: | Protein G Column |
| Presentation: | PBS, pH 7.2, 0.05% sodium azide. |
| Recommended Storage: | Long term: Add glycerol (40-50%) -20°C; Short term: +4°C |
| Antibody Usage Summary: | Immunohistochemistry: LS-B3162 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D2, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B3162 was determined to be 1:50. Function: Blocks the binding of aldosterone to the MR. |
| Antibody Uses: | Immunohistochemistry (IHC) (1:100), Immunohistochemistry - Paraffin (IHC-P) (1:50), Western blot (WB) (1:250) (Optimal dilution to be determined by the researcher) |
| Size: | 50 µl |


