NOS-1 Antibody

Nitric oxide synthases (NOS) are enzymes that catalyze the generation of nitric oxide (NO) from L-arginine and require nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor. At least three NOS isoforms have been identified: neuronal NOS (nNOS or NOS1 or bNOS), inducible NOS (iNOS or NOSII) and endothelial NOS (eNOS or NOS III). NOS-1 produces NO which is a messenger molecule with diverse functions throughout the body. NO behaves as a neurotransmitter in the brain and peripheral nervous system. Genetic variations of NOS1 gene are associated with susceptibility to infantile pyloric stenosis type 1 (IHPS1).