ND-630
- 貨號 Cat. No.
- 406952-5mg
- 規格 Size
- 5mg
- 品牌 Brand
- MedKoo
Description
ND-630, also known as GS-0976, NDI-010976, and firsocostat, is a potent ACC inhibitor. ND-630 nteracts within the ACC phosphopeptide acceptor and dimerization site to prevent dimerization and inhibit the enzymatic activity of both ACC isozymes, reduce fatty acid synthesis and stimulate fatty acid oxidation in cultured cells and in animals, and exhibit favorable drug-like properties. ND-630 reduces hepatic steatosis, improves insulin sensitivity, reduces weight gain without affecting food intake, and favorably affects dyslipidemia. When administered chronically to Zucker diabetic fatty rats, ND-630 reduces hepatic steatosis, improves glucose-stimulated insulin secretion, and reduces hemoglobin A1c (0.9% reduction).
Appearance:
Solid powder
Purity:
>98% (or refer to the Certificate of Analysis)
Certificate of Analysis:
View CoA: current batch, Lot#A7T12K19
QC Data:
View QC data: current batch, Lot#A7T12K19
Safety Data Sheet (SDS):
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:
Soluble in DMSO
Shelf Life:
>2 years if stored properly
Drug Formulation:
This drug may be formulated in DMSO
Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code:
2934.99.9001
