NCS-1 Antibody

Antibody Target :NCS-1

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Antibody Form: Affinity Purified Antibody

Immunogen Sequence: Synthetic peptide surrounding amino acid 180 of human NCS-1

Accession#: AAP97256

Gene ID: 23413

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) Protein A affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Species Reactivity: hu/rt

Application: WB

Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Rat kidney tissue lysate can be used as a positive control. The antibody recognizes ~24 kDa NCS-1 from samples of human and rat origins. Reactivity to other species has not been determined.

Storage Temp.: -20 °C

Shipping : gel pack

Shelf Life: 12 months

Handling: The antibody solution should be gently mixed before use.

Brief Background Descriptions: The neuronal calcium sensor (NCS) protein binds to calcium through EF-hand motifs, are expressed in neurons. They are implicated in the regulation of neurotransmitters released at the neuromuscular junctions. NCS-1 is widely distributed in the brain, spinal cord and dorsal root ganglia. It has been shown to regulate neurosecreation in a calcium-dependent manner, potentiates nitric oxide synthase activity. NCS-1 has been reserved to indicate the protein observed in humans and mammals.