Nalidixic acid
Chemical Compounds
- 貨號 Cat. No.
- M3249
- 規格 Size
- 1g
- 品牌 Brand
- No Brand
Description
Nalidixic acid (NegGram) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase. Evidence exists that the active metabolite, hydroxynalidixic acid, binds strongly, but reversibly, to DNA, interfering with synthesis of RNA and, consequently, with protein synthesis.
