Myelin P0 Protein Antibody

The Myelin P0 protein (MPZ) creates an extracellular membrane face to guide the wrapping process for ultimately compacting adjacent lamellae. MPZ is a single-pass type I membrane protein only found in peripheral nervous system Schwann cells. Defects in MPZ are the cause of Charcot-Marie-Tooth disease, an inherited peripheral nervous system disorder characterized by muscle and nerve atrophy.