MTR-1A Peptide

Melatonin receptor-1A (MTR-1A) is a high affinity receptor for melatonin, which mediates the reproductive and circadian actions of melatonin. MTR-1A activity is mediated by pertussis toxin sensitive G-proteins that inhibit adenylate cyclase activity. MTR-1A is expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). MTR-1A belongs to the G-protein coupled receptor 1 family.