MSH2 (1B3) Antibody

Antibodies

貨號 Cat. No.: 252617
規格 Size: 0.1 ml
品牌 Brand: Abbiotec
Application 應用: IHC 、 WB
Reactivity: Human

Description

MSH2 (DNA mismatch repair protein Msh2) is a component of the post-replicative DNA mismatch repair system (MMR). MSH2 forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) that bind to DNA mismatches and initiate DNA repair. Defects in MSH2 are the cause of hereditary nonpolyposis colorectal cancer type 1 and endometrial cancers.

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