Mouse TNFR1 / CD120a / TNFRSF1A Protein (Fc Tag)

Species : Mouse

Synonyms : CD120a,FPF,p55,p55-R,TNF-alphaR1,TNF-R,TNF-R-I,TNF-R1,TNF-R55,TNFalpha-R1,TNFAR,Tnfr-2,Tnfr1,TNFR60,TNFRI,TNFRp55

Host : HEK293 Cells

Purity :> 90 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized Mouse TNF-alpha (Cat:50349-MNAE) at 2 £gg/ml (100 £gl/well) can bind Mouse TNFRSF1AhFc (Cat:50496-M02H), the EC50?of Mouse TNFRSF1AhFc is 1.5-9.0 ng/mL.
2. Measured by its ability to inhibit the TNF£-mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 15-65 ng/mL in the presence of 0.1 ng/mL of recombinant mouse TNF£.