Mouse ROR2 / NTRKR2 Protein, Fc Tag

Source : 

Mouse ROR2, Fc Tag (RO2-M5253) is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Gly 403 (Accession # Q9Z138-1).

 

Molecule : ROR2

 

Synonyms : ROR2,NTRKR2

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : N/A

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 67.6 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 67.6 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : Tris with Glycine, Arginine and NaCl, pH7.5

 

Description :

Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

 

References :

(1) Liu Y., et al., 2007, Mol. Endocrinol. 21:3050-3061.
(2) Afzal A.R., et al., 2000, Nat. Genet. 25:419-422.
(3) van Bokhoven H., et al., 2000, Nat. Genet. 25:423-426.