Mouse Prothrombin

Localization: Plasma Plasma concentration: 100 μg/ml (1) Mode of action: Zymogen; precursor to the serine protease a-thrombin Molecular weight: 72,000 (1,4,5) Extinction coefficient: E 1 % 1 c m, 280 nm = 13.8 (human) (4) = 14.4 (bovine) (1) Isoelectric point: 4.7-4.9 (human) (6) 4.4-4.9 (bovine) (6) Structure: single chain, NH2-terminal gla domain, two kringle regions Percent carbohydrate: 8.2 % (human) (4) 10.0 % (bovine) (5) Post-translational modifications: ten gla residues (4,5)