Mouse Protein C

Localization: Plasma Plasma concentration: 4-5 μg/ml (human) (6) 5-10 μg/ml (bovine) (2) Mode of action: Zymogen; precursor to the serine protease activated protein C (APC) Molecular weight: 62,000 (human) (7) 58,000 (bovine) (7) Extinction coefficient: E 1 % 1 c m, 280 nm = 14.5 (human) (7) = 13.7 (bovine) (7) Isoelectric point: 4.4-4.8 (human) (8) 4.2-4.5 (bovine) (8) Structure: two chains, Mr=41,000 and 21,000, disulfide linked, NH2-terminal gla domain two EGF domains Percent carbohydrate: 23 % (human) (7) 14 % (bovine) (7) Post-translational modifications: eleven gla residues (bovine), nine gla residues (human), one β-hydroxyaspartate