Mouse polyclonal antibody to human TrpC5
Antibodies
- 貨號 Cat. No.
- M-916-50
- 規格 Size
- 50 µL
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Polyclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Short transient receptor potential channel 5; Htrp-5; Htrp5; TRPC5; TRP5
Antibody_Isotype
(Antibody only) :
Application_Details :
This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) :
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=404
Description (Long Description) :
It has been demonstrated that TrpC1 and TrpC5 are subunits of a heteromeric neuronal channel in mammalian brain. TrpC5 is thought to form a receptor-activatd non-selective permeant cation channel. It is probably operated by a phosphatidylinositol second messenger system activated by receptor kinases or G-protein coupled receptors. It has also been shown to be calcium-selective and it may be also activated by intracellular calcium store depletion. TrpC5 protein was shown to be present in hippocampal neuronal growth cones, neuronal cell bodies, areas consistent with new synapse formation, and cytoplasmic transport vesicles along neuronal processes. TrpC5 is expressed in brain with higher levels in fetal brain. Influxes of calcium via voltage-gated channels play a role in neuronal outgrowth and it was suggested that TrpC5 is a candidate for the regulation of calcium waves.
Expiry_Date :
12 months after purchase
Format (Form) :
Liquid. Storage buffer: 50% glycerol
Immunogen (Antigen) :Partial recombinant human TrpC5 [534-603] with a GST tag.
Kit_Components :
MSDS (File name) :
