Mouse polyclonal antibody to human Mam-3: whole serum
Antibodies
- 貨號 Cat. No.
- Mo-946-50
- 規格 Size
- 50 µL
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Polyclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Mastermind-like protein 3; MAmL3; KIAA1816
Antibody_Isotype
(Antibody only) : Mixed
Application_Details :
This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) :
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=425
Description (Long Description) :
Mam-3 acts as a transcriptional coactivator for NOTCH proteins. It has been shown to amplify NOTCH-induced transcription of HES1. Mam-3 is a nuclear protein that contains an N-terminal basic domain, a central acidic domain, and a C-terminal acidic domain. It interacts through its N-terminal region with the ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. It forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa. The C-terminal domain is required for transcriptional activation. Mam-3 belongs to the mastermind family.
Expiry_Date :
12 months after purchase
Format (Form) :
Liquid. 50% glycerol
Immunogen (Antigen) :Partial recombinant human MAM-3 (1024-1131) with a GST tag.
Kit_Components :
MSDS (File name) :
