Mouse monoclonal to human Transcription factor HES-1 [4D9]: IgG

Antibodies

貨號 Cat. No.
M-841-100
規格 Size
100 µg
品牌 Brand
Biosensis
Application 應用
ELISA 、 WB
Reactivity
Human
Host
Mouse
Clonality
Monoclonal

Description




ZZZZ_Status (Active, Disc) : Active


 

AA_Supplier Name : Biosensis


 

Alternative_Name (Other Names) :


Hairy and enhancer of split 1; Hairy-like; HHL; Hairy homolog; HES1; HL; HRY


 

Antibody_Isotype
(Antibody only) :


 

Application_Details :


This antibody is recommended for WB, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.


 

Background_Info :


 

Clone_Name
(AB only, monoclonals) : 4D9


 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=328


 

Description (Long Description) : 


Transcription factor HES-1 is a transcriptional repressor of genes that require a basic helix-loop-helix protein for their transcription. It needs to form a complex with a corepressor protein (Groucho) to repress transcription. Transcription factor HES-1 has a particular type of basic domain which contains a helix-interrupting proline, that binds to the N-box (CACNAG) rather than the canonical E-box (CANNTG). It also consists of a C-terminal WRPW motif that is necessary for the interaction with Groucho. It localises to the nucleus.


 

Expiry_Date : 


12 months after purchase

 

Format (Form) : 


Lyophilized from PBS pH 7.3

 

Immunogen (Antigen) :Partial recombinant protein of human Transcription factor HES-1 (aa 36 to 143) with a GST tag.


 

Kit_Components :


 

MSDS (File name) :


 



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