Mouse monoclonal to human protein kinase minibrain homolog [7D10]: IgG
Antibodies
- 貨號 Cat. No.
- M-829-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Mouse 、 Rat
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Dual specificity tyrosine-phosphorylation-regulated kinase 1A; MNBH; HP86; Dual specificity YAK1-related kinase; hMNB; DYRK1A
Antibody_Isotype
(Antibody only) :
Application_Details :
Direct and sandwich ELISA and WB are recommended for this antibody. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 7D10
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=311
Description (Long Description) :
Protein kinase minibrain homolog phosphorylates serine, threonine and tyrosine residues in its sequence as well as in exogenous substrates. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. There are 5 named isoforms produced by alternative splicing. It is expressed ubiquitously with highest levels in skeletal muscle, testis, fetal lung and kidney, and in the developing central nervous system. It localises to the nucleus speckle. This protein is overexpressed 1.5-fold in fetal Down syndrome brain and considered a strong candidate for learning defects associated with Down syndrome. It belongs to the protein kinase superfamily, CMGC ser/Thr protein kinase family and MNB/DYRK subfamilly.
Expiry_Date :
12 months when stored at -20°C
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial recombinant protein of human protein kinase minibrain homolog (aa 674 to 763) with a GST tag.
Kit_Components :
MSDS (File name) :
