Mouse monoclonal antibody to proNGF (30-41), [Clone BS312]: IgG

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Pro-brain nerve growth factor; proNGF; NGF

 

Antibody_Isotype
(Antibody only) : IgG2b, lambda-light chain

 

Application_Details :

Flow Cytometry (2 µg/ 10^6 cells). Immunocytochemistry (1-2 ug/mL), Western Blotting (1-2 ug/mL). Other applications not yet tested. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : BS312

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1552

 

Description (Long Description) : 

Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released.

 

Expiry_Date : 

12 months after purchase if unopened

 

Format (Form) : 

Lyophilized from a solution containing PBS buffer pH 7.4 with 3% trehalose, without preservatives.

 

Immunogen (Antigen) :A synthetic peptide (C-HTIPQAHWTKLQ, aa: 30-41) of human proNGF protein has been used as the immunogen. The sequence is located on the pro-domain of the proNGF full-length protein and is 80% homologous to mouse and rat proNGF.

 

Kit_Components :

 

MSDS (File name) :